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Portrait of Susan Uptain, Ph.D.

Susan Uptain, Ph.D.

Head of Project Team Leadership and Regulatory

Susan is passionate about leading teams to bring new medicines to patients.

About

In her role as Head of Project Team Leadership and Regulatory, Susan provides oversight and direction for Calico’s drug discovery and development programs as they transition from candidate nomination through IND filing and clinical proof of concept. She brings extensive expertise in drug development and program leadership to her work advancing Calico’s drug development pipeline. Her work in regulatory affairs and quality management ensures each program’s strategy aligns with Calico’s long-term mission to develop therapies addressing aging and age-related diseases.

Before joining Calico, Susan held senior leadership roles at Xilio Therapeutics, Takeda, Shire, Baxalta, and Merck where she guided regulatory strategy and oversaw program direction and quality management initiatives. With more than 20 years of experience in the biopharmaceutical industry, she has contributed to the development of 15 therapies from pre-IND though patent expiry during her career.

Education:
  • Ph.D. in Molecular and Cellular Biology, University of California, Berkeley
  • B.S., Biology and Chemistry, Wayne State University